How to Read and Use an AGP Report: A Complete Guide to Interpreting Continuous Glucose Monitoring Data

1. What Is AGP and Why Was It Developed

  • AGP (Ambulatory Glucose Profile) is a standardized graphical report based on CGM data.
  • Developed in 1987 to simplify glucose trend interpretation.
  • Officially standardized in 2008 by the International Diabetes Center.
  • Endorsed in CGM consensus guidelines since 2013 and included in ADA Standards since 2020.
  • Purpose: Make glucose data more visual, comparable, and clinically useful.

2. Structure of the AGP Report

The AGP report includes three core sections:
  • Glucose Metrics Summary: Quantitative indicators for glycemic control.
  • 24-hour Glucose Profile Graph: Visual trend showing average daily patterns.
  • Daily Views: Help identify intra-day variability and outliers.
Focus: The metrics summary gives the clearest overview of overall glycemic status.

3. Understanding the 10 Key Metrics

Grouped into three categories:
A. Data Quality Metrics
  • Wear Days & Sensor Activity % → Reliable CGM data requires ≥14 days and ≥70% active time.
B. Glucose Control Overview
  • Mean Glucose
  • GMI (Glucose Management Indicator): Replaces eA1c; target <7%.
  • Glycemic Variability (CV%): Target <36% to reduce complication risks.
C. Range-Based Metrics
  • TIR (Time in Range: 70–180 mg/dL): Target ≥70%.
  • TAR (Time Above Range): >180 and >250 mg/dL tracked.
  • TBR (Time Below Range): <70 and <54 mg/dL tracked. → Use all three together to evaluate risks of both hyper- and hypoglycemia.

4. How to Adjust Targets for Different Populations

  • Standard targets: TIR ≥70%, TBR <4%, GMI <7% (most adults with T1 or T2 diabetes)
  • Elderly or high-risk individuals: TIR ≥50%, TBR <1%
  • Pregnancy (Type 1 Diabetes): TIR ≥70%, target range tightened to 63–140 mg/dL
  • Gestational or T2D in pregnancy: Guidelines still evolving; no fixed TIR yet
Always tailor interpretation based on age, condition, and comorbidities.